Basic Concepts in Mathematical Biology

Build mathematical models for biological rhythms and dynamics

Rating (4.6) Price Free plan available on FutureLearn
Created by Professor Myung
Platform: FutureLearn Topic: Math Science Skills: Differential Equations Mathematical Modeling Nonlinear Dynamics

Basic Concepts in Mathematical Biology introduces mathematical modelling approaches for dynamic biological phenomena, focusing on differential equations and nonlinear dynamics to reveal patterns in systems ranging from neural firing to gene expression and circadian rhythms.

The course combines phase-space visualization, oscillatory-systems analysis, and synchronization theory with practical examples so learners with a calculus background can build transferable quantitative skills for neuroscience and physiological modelling.

At a Glance

Basic Concepts in Mathematical Biology is an online course taught by Professor Myung of Taipei Medical University that introduces how differential equations and nonlinear dynamics describe physiological and cellular processes.

It broadly covers mathematical modeling fundamentals, phase-space visualization, oscillatory systems and limit cycles, and synchronization as applied to rhythms like neural firing and circadian clocks.

Level Intermediate
Rating 4.6 out of 5
Duration 4+ weeks
Languages English
Certificate Certificate of achievement available
Access Free access during the course with option to upgrade for extended access and certificate; also available via FutureLearn subscription
Course includes
  • Bite-sized videos, articles, and audio
  • Practical activities and assessments
  • Peer discussion and community interaction
  • Progress tracking and completion checks
Price Free to access limited content; optional paid upgrade for certificate and extended access; also available with subscription

What This Course Teaches

By course end, learners will gain measurable competencies for modeling and analysing dynamic biological systems, from constructing differential-equation models to evaluating rhythmic behaviour and synchronization. Competencies include applying mathematical models to biological and neural systems and analysing oscillatory stability and synchronization using nonlinear dynamics methods.

Mathematical Modeling
Apply basic principles of mathematical modeling to biological and neural systems.
Differential Equations
Apply differential equations to model biological change and oscillations.
Synchronization & Stability
Investigate synchronization and analyse the stability of oscillations using nonlinear dynamics tools.
Toy Models
Describe how simple toy models represent gene expression oscillations and action potential generation.
Quantitative Reasoning
Develop foundational mathematical thinking and integrate quantitative biological data into analyses.

How the Course Is Structured

The course is organised as a short, focused programme spanning 9 modules delivered over 4 weeks, with each week grouping sessions on modelling, oscillations, nonlinear dynamics, and synchronization.

Course content is arranged sequentially as individual syllabus sessions so learners progress module-by-module toward a final review and feedback session.

Curriculum overview

01 Fundamentals of Mathematical Biology and Linear Kinetics

Evaluates biological dynamism using differential equations and linear kinetics, using analogies such as a water-tank to contextualise equilibrium and rate processes.

02 Stability, Chaos, and Real-World Applications in Nonlinear Dynamics

Introduces stability, equilibrium, and chaotic behaviour in nonlinear systems and demonstrates how small parameter changes can produce complex outcomes in biological contexts.

03 Understand Oscillations and Differential Equation Models

Covers how oscillatory behaviour is modelled with differential equations and how dynamic variables describe rhythmic patterns in biological systems.

04 Visualize Biological Dynamics in Phase Space

Explores phase space, vector fields, and trajectory visualisation as tools to understand how system states evolve over time.

05 Explore Nonlinear Dynamics in Biological Systems

Examines nonlinear transformations and their role in producing complex, often counterintuitive behaviours observed in biological models.

06 Analyze Stability and Cycles in Nonlinear Systems

Focuses on vector fields, nullclines, limit cycles and bifurcations to analyse stability, sustained oscillations, and transitions in system behaviour.

07 Basic Concepts of Synchronization

Introduces mathematical concepts of synchronization, demonstrates different types of coupled oscillators, and explains structures such as the Arnold tongue.

08 Circadian Clocks and Cellular Models

Applies synchronization models like the Kuramoto model to cellular circadian clocks and examines double-plot actograms to study population-level timing.

09 Course Feedback and Final Review

Provides an opportunity to review key concepts from the course, reflect on learning progress, and submit feedback on the course experience.

Audience & Requirements

This course targets graduate students, researchers, and advanced undergraduates in biology, neuroscience, and related life sciences who need mathematical tools to model dynamic biological processes.

It is best suited to learners who are bridging quantitative methods and biology and already have a calculus background.

Who It’s For
  • Graduate students and researchers in biology or neuroscience seeking modelling skills.
  • Early-career scientists who need to analyse rhythmic physiological or cellular data.
  • Interdisciplinary researchers bridging mathematics and life sciences.
  • Coursework or exam candidates needing focused training in dynamical systems for biology.
What You’ll Need
  • Calculus and basic familiarity with differential equations.
  • Undergraduate-level understanding of biology or neuroscience concepts.
  • Comfort reading mathematical notation and following quantitative arguments.

Final Verdict

Given its strong user rating, broad uptake, and the availability of a verified certificate via an optional upgrade or subscription, this course is a cost-effective way to acquire practical mathematical modelling skills for biological systems.

It is particularly worthwhile for learners who already meet the calculus prerequisite and want a compact, application-focused introduction to differential equations, oscillations, and synchronization in biology; those without the necessary math background should prepare with a targeted calculus or differential-equations refresher first.

Course Details

Platform FutureLearn
Rating (4.6)
Level Intermediate
Language English
Price Free plan available
View on FutureLearn